Role of HALP score in predicting short term outcomes after surgery in esophago-gastric cancers

Authors

  • Ashish Kharel Dept. of Surgical oncology, thoracic surgery unit. B P Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal
  • Binay Thakur Dept. of Surgical oncology, thoracic surgery unit. B P Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal
  • Sagar Khatiwada Dept. of Surgical oncology, thoracic surgery unit. B P Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal
  • Manoj Tiwari Dept. of Surgical oncology, thoracic surgery unit. B P Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal
  • Shachee Bhattarai Dept. of Surgical oncology, thoracic surgery unit. B P Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal
  • Mahesh Mani Adhikari Dept. of Surgical oncology, thoracic surgery unit. B P Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal
  • Sandeep Sapkota Dept. of Surgical oncology, thoracic surgery unit. B P Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal
  • Shrijana Thapa Dept. of Surgical oncology, thoracic surgery unit. B P Koirala Memorial Cancer Hospital, Bharatpur, Chitwan, Nepal

DOI:

https://doi.org/10.3126/njc.v9i1.77095

Keywords:

Esophageal cancer, Esophagectomy, HALP score

Abstract

Background: Esophago-gastric cancers are common cancers with poor prognosis. Radical surgery offers the best hope for long term survival but is associated with increased short-term morbidity and mortality. There is a need for a simple scoring system that helps in estimating the short-term prognosis of the patient after undergoing surgery for these cancers. Hemoglobin, Albumin, Lymphocytes, Platelets (HALP) score is such a scoring system that has recently been developed. The aim of this study was to evaluate the role of HALP score in predicting short term outcomes after surgery in esophago- gastric cancers.

Methods: We conducted a prospective study of all patients with esophago-gastric cancers undergoing curative intent surgery in the surgical oncology department. The optimal HALP cut-off point was evaluated using Receiver operating characteristics (ROC) analysis and the cohort was divided into Low and High HALP groups, which were then further analyzed.

Results: The mean age was 61.52 ± 9.07 years. Of these 17 (54.8%) were male and 14 (45.2%) were female. Squamous cell carcinoma was the more common histology. The optimal cut-off value of HALP was 38.0 with a sensitivity of 86.7% and specificity of 87.5%. Low HALP was significantly associated with Anastomotic leak, SSI, overall mortality and prolonged hospital stay.

Conclusion: HALP score can be a good prognostic indicator for patients with esophago-gastric cancers undergoing curative resection.

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Published

2025-04-01

How to Cite

Kharel, A., Thakur, B., Khatiwada, S., Tiwari, M., Bhattarai, S., Adhikari, M. M., … Thapa, S. (2025). Role of HALP score in predicting short term outcomes after surgery in esophago-gastric cancers. Nepalese Journal of Cancer, 9(1), 65–70. https://doi.org/10.3126/njc.v9i1.77095

Issue

Vol. 9 No. 1 (2025)

Section

Original Articles

License

Copyright (c) 2025 Nepalese Journal of Cancer

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