Study of Comparison of conventional ultrasound, RMI 4 score and CT imaging in diagnosis of Ovarian Cancer confirmed by surgical-pathological findings

Abstract

Background: Ovarian cancer; 5^th commonest cancer among Nepalese women is the leading cause of gynecologic cancer related death. Proper diagnostic studies therefore assist Gyne-oncologist for appropriate surgery and chemotherapeutic planning, there by optimizing the patient prognosis. Objective of current study was to compare ultrasonography imaging, CT imaging, CA 125 value, RMI 4 score and surgical staging in diagnosis of ovarian cancer correlated with histo-pathological findings.

Materials and Methods: The study was retrospective observational study, carried out between 14^th April 2019 to 16^th October 2021, in the department of surgical oncology (Gynecology oncology unit), B.P Koirala Memorial Cancer Hospital, Bharatpur.

Results: 53 patient data were included in the observation. The efficacy of Ultrasound (sensitivity-90.90%, Specificity-60%) and CT (sensitivity-100%, specificity-65%) gave the best result in non-invasive investigations; whereas surgical staging (sensitivity- 96.96%, specificity- 90%) gave the better result when invasive modalities were considered. RMI 4 score had sensitivity 96.96% and specificity 60%.

Conclusion: All modalities had good diagnostic performances and complemented each other in further defining the characterization of the ovarian mass, local spread and distant tumor dissemination.