Phytochemical Screening, GC-MS Analysis and Biological Activities of Extracts of Artemisia vulgaris Linn.

Authors

  • Rashma Chaudhary Department of Chemistry, Amrit Campus, Institute of Science and Technology, Tribhuvan University, Lainchaur, Kathmandu, Nepal
  • Binita Maharjan Department of Chemistry, Amrit Campus, Institute of Science and Technology, Tribhuvan University, Lainchaur, Kathmandu, Nepal
  • Samjhana Bharati Department of Chemistry, Amrit Campus, Institute of Science and Technology, Tribhuvan University, Lainchaur, Kathmandu, Nepal
  • Timila Shrestha Department of Chemistry, Amrit Campus, Institute of Science and Technology, Tribhuvan University, Lainchaur, Kathmandu, Nepal
  • Pawan Kumar Mishra Department of Chemistry, Tri-Chandra Multiple Campus, Institute of Science and Technology, Tribhuvan University, Ghantaghar, Kathmandu, Nepal
  • Sangita Karanjit Institute of Biomedical Sciences, Graduate School of Pharmaceutical Sciences, Tokushima University Shomachi 1-78, Tokushima, 770-8505 Japan
  • Deval Prasad Bhattarai Department of Chemistry, Amrit Campus, Institute of Science and Technology, Tribhuvan University, Lainchaur, Kathmandu, Nepal
  • Puspa Lal Homagai Department of Chemistry, Amrit Campus, Institute of Science and Technology, Tribhuvan University, Lainchaur, Kathmandu, Nepal
  • Ram Lal (Swagat) Shrestha Department of Chemistry, Amrit Campus, Institute of Science and Technology, Tribhuvan University, Lainchaur, Kathmandu, Nepal; Institute of Natural Resources Innovation, Kalimati, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/arj.v2i01.40743

Keywords:

Artemisia vulgaris, Phytochemical screening, GC-MS, Biological Activity

Abstract

The aerial parts of Artemisia vulgaris were subjected for successive extraction in solvents methanol, hexane and chloroform, respectively, and compounds present in extract were analysed by GC-MS analysis 12 different compounds were found in chloroform extract in which Germacrene was found most abundantly (33.84%). Chloroform extract showed strong antibacterial activity, which was examined against 6 bacteria using the disc diffusion method. The IC50 value of chloroform extract accounted for 1.50 mg/mL. The TPC content of the extract was found to be 87.75 mg gallic acid equivalent/g of dry extract, whereas TFC content was found to be 47.25 mg quercetin equivalent/g of dry extract and exhibited LC50 value of 0.18 mg/mL.

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Published

2021-11-17

How to Cite

Chaudhary, R., Maharjan, B., Bharati, S., Shrestha, T., Mishra, P. K., Karanjit, S., Bhattarai, D. P., Homagai, P. L., & Shrestha , R. L. S. (2021). Phytochemical Screening, GC-MS Analysis and Biological Activities of Extracts of Artemisia vulgaris Linn. Amrit Research Journal, 2(01), 83–92. https://doi.org/10.3126/arj.v2i01.40743

Issue

Vol. 2 No. 01 (2021)

Section

Articles