An Emerging Zoonosis of Public Health Concern: A Comprehensive Review on Nipah Virus Infection

Authors

  • Kripa Chimire Gandaki Medical College, Pokhra, Nepal
  • Rajeshwar Reddy Kasarla Universal College of Medical Sciences, Bhairahawa, Nepal
  • Shristi Raut Adhikari Institute of Medicine, Kathmandu, Nepal
  • Laxmi Pathak Universal College of Medical Sciences, Bhairahawa, Nepal

DOI:

https://doi.org/10.3126/jucms.v10i01.47249

Keywords:

Emerging zoonosis, Encephalitis, Nipah virus infection

Abstract

Nipah virus (NiV) infection is an emerging zoonotic disease, which causes encephalitis and respiratory infections in humans with high mortality rate. Bats (Pteropus) are the natural hosts for for Nipah virus. The infection is transmitted from bats (Pteropus) to pigs and from pigs to humans or human-to-human. Clinical symptoms include fever, headache, dizziness, vomiting followed by drowsiness, disorientation, mental confusion, and neurological signs that indicate acute encephalitis. Due to lack of vaccines and effective antiviral drugs, and diagnostics, NiV infection poses a serious public health concern. The knowledge and scientific information on Nipah virus infection is still unknown or relatively limited to many clinicians, and received little attention; hence this comprehensive review of Nipah virus infection is undertaken to highlight its importance and further research.

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Author Biographies

Kripa Chimire, Gandaki Medical College, Pokhra, Nepal

Department of Microbiology

Rajeshwar Reddy Kasarla, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of microbiology

Shristi Raut Adhikari, Institute of Medicine, Kathmandu, Nepal

Department of Microbiology

Laxmi Pathak, Universal College of Medical Sciences, Bhairahawa, Nepal

Department of Anesthesiology and Critical Care Medicine

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Published

2022-08-09

How to Cite

Chimire, K., Kasarla, R. R., Adhikari, S. R., & Pathak, L. (2022). An Emerging Zoonosis of Public Health Concern: A Comprehensive Review on Nipah Virus Infection. Journal of Universal College of Medical Sciences, 10(01), 71–76. https://doi.org/10.3126/jucms.v10i01.47249

Issue

Vol. 10 No. 01 (2022): Issue 25

Section

Review Articles

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