Antibacterial Potential of the Methanol Stem Bark Extract of Stachytarpheta Indica

Authors

  • Christian Godwin Akuodor Dept. of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Development, P.M.B 21 Garki, Abuja,
  • Monday Pius Udia Dept. of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Development, P.M.B 21 Garki, Abuja,
  • Charles Emeka Udenze Dept. of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Development, P.M.B 21 Garki, Abuja,
  • John Onyemaechi Ogbonna Dept. of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Development, P.M.B 21 Garki, Abuja,

DOI:

https://doi.org/10.3126/ajms.v4i4.8248

Keywords:

Antibacterial agent, Stachytarpheta indica, Medicina plan, Stem bark, Methanol, in vitro

Abstract

Objective: There is increasing need for potent antimicrobial agents to tackle the problem of diseases in man. In view of this, the activities of methanol stem bark extract of Stachytarpheta indica was evaluated against some disease causing microorganisms.

Method: The activity of the extract against S. aureus, P.aeruginosa, E. coli, S. typhi and Shigella spp was determined using agar diffusion technique.

Results: The methanol stem bark extract demonstrated significant activity against the test organisms. The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the stem bark extract ranged from 12-60 μg/ml.

Conclusion: Further isolation of active compound responsible for the antibacterial activity could be the potential sources of new antibacterial agents.

Asian Journal of Medical Science, Volume-4 (2013), Pages 5-10

DOI: http://dx.doi.org/10.3126/ajms.v4i4.8248

 

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Author Biography

Christian Godwin Akuodor, Dept. of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Development, P.M.B 21 Garki, Abuja,

Research Fellow

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Published

2013-08-11

How to Cite

Akuodor, C. G., Udia, M. P., Udenze, C. E., & Ogbonna, J. O. (2013). Antibacterial Potential of the Methanol Stem Bark Extract of Stachytarpheta Indica. Asian Journal of Medical Sciences, 4(4), 5–10. https://doi.org/10.3126/ajms.v4i4.8248

Issue

Vol. 4 No. 4 (2013)

Section

Original Articles

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