Bacteriological profile of blood stream infections among febrile patients attending a tertiary care centre of Western Nepal

Authors

  • Dharm Raj Bhatta Manipal College of Medical sciences, Pokhara
  • Abhishek Gaur Manipal College of Medical sciences, Pokhara
  • HS Supram Manipal College of Medical sciences, Pokhara

DOI:

https://doi.org/10.3126/ajms.v4i3.8165

Keywords:

Blood stream infections, enteric fever, Escherichia coli, Pseudomonas aeruginosa, Salmonella paratyphi A.

Abstract

Background Blood stream infections (BSI) are significant cause of morbidity and mortality in the world. This study was conducted to determine the common bacterial agents associated with BSI with their antimicrobial susceptibility patterns in a tertiary care centre in the Western region of Nepal.

Method This cross-sectional study was conducted for a period of two years from May 2010 to May 2012. All patients with fever (temperature ≥ 38°C) were included in the study.

Results A total of 4,145 patients with febrile illness were included in this study, bacterial agents were isolated in 251 (6%) cases. Common bacterial isolates were Salmonella spp., Klebsiella pneumoniae, Escherichia coli, Pseudomonas species, Acinetobacter species, Staphylococcus aureus and Coagulase negative Staphylococci. Paratyphoid fever (Caused by S. Paratyphi A) is more common than typhoid fever. The members of Enterobacteriaceae were found to be resistant to ampicillin and cefazolin. Majority of the nonfermenters were found to be sensitive to most antibiotics. Gentamicin and Ciprofloxacin were sensitive to majority of gram positive bacteria.

Conclusion Gram-negative bacteria were the predominant causes of BSIs. The occurrence of drug resistance among the isolated bacteria is of great concern. Imipenem showed 100% sensitivity against Pseudomonas aeruginosa indicating lack or low level of MBL activity.

DOI: http://dx.doi.org/10.3126/ajms.v4i3.8165

Asian Journal of Medical Sciences 4(2013) 92-98

Downloads

Download data is not yet available.
Abstract
986
PDF
819

Author Biographies

Dharm Raj Bhatta, Manipal College of Medical sciences, Pokhara

Lecturer, Department of Microbiology

Abhishek Gaur, Manipal College of Medical sciences, Pokhara

Assistant Professor, Department of Microbiology

HS Supram, Manipal College of Medical sciences, Pokhara

Lecturer, Department of Microbiology

Downloads

Additional Files

Published

2013-06-20

How to Cite

Bhatta, D. R., Gaur, A., & Supram, H. (2013). Bacteriological profile of blood stream infections among febrile patients attending a tertiary care centre of Western Nepal. Asian Journal of Medical Sciences, 4(3), 92–98. https://doi.org/10.3126/ajms.v4i3.8165

Issue

Vol. 4 No. 3 (2013)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).