Evaluation of SARS Cov-2 disease epidemiology, clinical and diagnostic profile-a regional study from tertiary care center of North India

Authors

DOI:

https://doi.org/10.3126/ajms.v15i3.60337

Keywords:

Cartridge-based nucleic acid amplification test; Indian Council of Medical Research; Influenza-like illness; Real-time polymerase chain reaction; Severe acute respiratory illnesses; Severe acute respiratory syndrome corona virus-2; World Health Organization

Abstract

Background: A novel coronavirus severe acute respiratory syndrome coronavirus-2 (SARSCoV-2) that emerged in China in December 2019 has spread rapidly globally to many countries including India and World Health Organization declared it as a pandemic on March 11th, 2020.

Aims and Objectives: The current study endeavors to determine the SARS-CoV-2 positivity rate as well as epidemiological, clinical, and diagnostic profiles from the second wave.

Materials and Methods: We performed a retrospective analysis of all suspected COVID-19 cases from January 2021 to October 2021 presenting at a large testing center for SARS-CoV-2 infection by real-time polymerase chain reaction (RT-PCR). Descriptive analysis has been performed for profiling of clinical-epidemiological aspects of suspected cases.

Results: A total of 694427 participants were enrolled during the study from January 2021 to October 2021. Overall RT-PCR positivity rate was found to be 1.7% in the year 2021 and the positivity was maximum in April 2021 which represents the second wave of COVID-19 infection in India. In the study population, more than half (57.07%) of the persons screened for COVID-19 infection were between 21 and 40 years of age, and about two-thirds (65.20%) of the persons screened were male followed by 34.79% were female.

Conclusions: SARS-CoV-2 poses a high burden of infections in the community. Males had a higher RT-PCR detection rate as compared to females. The younger age group (<20 years) expressed the least RT-PCR positivity rate and the elderly population (>80 years) expressed the highest positivity rate.

Downloads

Download data is not yet available.
Abstract
172
PDF
108

Downloads

Published

2024-03-01 — Updated on 2024-04-06

Versions

How to Cite

Arti Agrawal, Astha, Vikas Kumar, Dharmendra Kumar, Neelika Tripathi, & Sanjeev Kumar. (2024). Evaluation of SARS Cov-2 disease epidemiology, clinical and diagnostic profile-a regional study from tertiary care center of North India. Asian Journal of Medical Sciences, 15(3), 3–8. https://doi.org/10.3126/ajms.v15i3.60337 (Original work published March 1, 2024)

Issue

Vol. 15 No. 3 (2024)

Section

Original Articles

License

Copyright (c) 2024 Asian Journal of Medical Sciences

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).