Triple Negative Breast Cancer-An Overview and Review of Literature

Authors

  • Amit Gupta Dept. of Surgery, University College of Medical Sciences & Associated Guru Teg Bahadur Hospital
  • Jyotika Jain Delhi State Cancer Institute
  • Ajay Kumar Dept. of Surgery, University College of Medical Sciences & Associated Guru Teg Bahadur Hospital
  • Sunil Kumar Dept. of Surgery, University College of Medical Sciences & Associated Guru Teg Bahadur Hospital
  • Neelam Wadhwa Dept. of Pathology, University College of Medical Sciences & Associated Guru Teg Bahadur Hospital

DOI:

https://doi.org/10.3126/ajms.v3i2.5384

Keywords:

breast cancer, triple-negative, estrogen progesterone receptor (PR), Her2/neu receptor

Abstract

Triple-negative breast cancer refers to a specific subtype of breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) or Her2/neu. About 12-17 % of ca breast  have triple negative ca breast This subtype of breast cancer is clinically characterized as more aggressive and less responsive to standard treatment and associated with overall poorer prognosis. Chemotherapy is the choice of systemic therapy for triple-negative tumors. They are more susceptible to non-receptor mediated therapies than other tumors. A number of new strategies are currently being tested in clinical trials.

DOI: http://dx.doi.org/10.3126/ajms.v3i2.5384

Asian Journal of Medical Sciences 3(2012) 16-20

Downloads

Download data is not yet available.
Abstract
1065
PDF
1520

Downloads

Published

2013-02-26

How to Cite

Gupta, A., Jain, J., Kumar, A., Kumar, S., & Wadhwa, N. (2013). Triple Negative Breast Cancer-An Overview and Review of Literature. Asian Journal of Medical Sciences, 3(2), 16–20. https://doi.org/10.3126/ajms.v3i2.5384

Issue

Vol. 3 No. 2 (2012)

Section

Review Articles

License

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).