Evaluation of serum mineral micronutrients (Zn, Cu, Fe, Mg) and their correlation with clinical parameters (gingival index, probing pocket depth, clinical attachment loss) in chronic periodontitis patients

Authors

  • Anusree Raju Consultant Periodontist, Quilon Orthodontic Center, Kollam, Kerala, India https://orcid.org/0009-0004-6019-0675
  • Sanjeev Ravindran Professor and Head, Department of Periodontics and Implantology, PSM College of Dental Science and Research, Thrissur, Kerala, India
  • Shyamala Devi MP Professor, Department of Periodontics and Implantology, PSM College of Dental Science and Research, Thrissur, Kerala, India https://orcid.org/0009-0008-0142-4151
  • Shaheena KP Senior Lecturer, Department of Periodontics and Implantology, PSM College of Dental Science and Research, Thrissur, Kerala, India https://orcid.org/0009-0007-0343-7178
  • Anusha Anish Deputy Research Director, Department of Central Research Laboratory, PSM College of Dental Science and Research, Thrissur, Kerala, India https://orcid.org/0009-0005-7899-0707
  • Hari S Pillai Principal, Department of Central Research Laboratory, PSM College of Dental Science and Research, Thrissur, Kerala, India https://orcid.org/0009-0008-2724-1871
  • Annamala PT Research Director, Department of Central Research Laboratory, PSM College of Dental Science and Research, Thrissur, Kerala, India https://orcid.org/0009-0009-0999-4877

DOI:

https://doi.org/10.3126/ajms.v14i6.51478

Keywords:

Mineral micronutrients; Iron; Copper; Zinc; Magnesium; Periodontitis

Abstract

Background: Nutrition especially micro-mineral nutrients plays a major role in the etiology of chronic periodontitis. Serum levels of micro-mineral nutrients can be used as markers for the incidence of periodontitis and may also be used as indicators for dietary supplementation.

Aims and Objectives: The aim of the study was to estimate the serum levels of Zn, Cu, Fe, and Mg of chronic periodontitis patients and normal healthy controls., to measure the clinical parameters (gingival index, probing pocket depth [PPD], and clinical attachment loss) in chronic periodontitis patients and normal healthy controls., to compare the levels of serum Zn, Cu, Fe, and Mg levels of chronic periodontitis patients and healthy controls and to correlate the levels of serum micronutrients with clinical parameters (gingival index, PPD, and clinical attachment loss) in chronic periodontitis patients and healthy controls.

Materials and Methods: A total of 110 subjects, 55 subjects with chronic periodontitis and 55 healthy control subjects in the age group 35–65 years were selected for the study. Serum micronutrient levels of Cu, Fe, Zn, Mg, and the clinical parameters were measured.

Results: Serum concentrations of Cu and Fe showed statistically significant increase and serum Zn and Mg showed a significant decrease in peridontitis patients as compared to normal healthy controls. Copper and Fe showed a significant positive correlation and Zn and Mg showed a significant negative correlation with clinical parameters (gingival index, PPD, and clinical attachment loss).

Conclusion: The present study supports and extends the view that the assessment of serum mineral micronutrient can serve as possible biomarkers or indicators for an inflammatory condition like chronic periodontitis.

Downloads

Download data is not yet available.
Abstract
93
PDF
160

Downloads

Published

2023-06-01

How to Cite

Anusree Raju, Sanjeev Ravindran, Shyamala Devi MP, Shaheena KP, Anusha Anish, Hari S Pillai, & Annamala PT. (2023). Evaluation of serum mineral micronutrients (Zn, Cu, Fe, Mg) and their correlation with clinical parameters (gingival index, probing pocket depth, clinical attachment loss) in chronic periodontitis patients. Asian Journal of Medical Sciences, 14(6), 233–242. https://doi.org/10.3126/ajms.v14i6.51478

Issue

Vol. 14 No. 6 (2023)

Section

Original Articles

License

Copyright (c) 2023 Asian Journal of Medical Sciences

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).