A study on oxidized-LDL cholesterol in normolipidemic retinal vein occlusion

Authors

DOI:

https://doi.org/10.3126/ajms.v14i5.51305

Keywords:

Oxidized-LDL cholesterol; LDL cholesterol; Retinal vein occlusion

Abstract

Background: Oxidized low-density lipoprotein (ox-LDL) has been implicated in atherosclerotic cardiovascular disease. Arteriolosclerosis is an important causative factor for retinal vein occlusion (RVO). Till, date there is dearth of literature on ox-LDL and RVO.

Aims and Objectives: The objectives of this study were to see whether ox-LDL cholesterol is an independent risk factor in RVO with normal lipid profile.

Materials and Methods: Lipid profiles and ox-LDL levels were assayed in 122 adult unilateral RVO cases and 142 age and sex matched controls in this 1 year old case–control study.

Results: ox-LDL cholesterol levels were significantly elevated in RVO cases than controls (54.5±6.1 in cases vs. 36.6±5.6 in controls, P<0.01), although serum lipid profiles were normal in both cases and controls.

Conclusion: The ox-LDL-induced atherosclerosis may be responsible for the retinal venous occlusion in absence of other risk factors. Hence, screening for ox-LDL in RVO patients should be worth considering especially in patients with normal lipid profiles.

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Published

2023-05-01

How to Cite

Kapil Deb Lahiri, Gupta, A. K. ., & Utpal Kumar Biswas. (2023). A study on oxidized-LDL cholesterol in normolipidemic retinal vein occlusion. Asian Journal of Medical Sciences, 14(5), 71–74. https://doi.org/10.3126/ajms.v14i5.51305

Issue

Vol. 14 No. 5 (2023)

Section

Original Articles

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Copyright (c) 2023 Asian Journal of Medical Sciences

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