Transcranial Doppler in hypoxic-ischemic encephalopathy babies as a prognostic marker in the short-term outcome
DOI:
https://doi.org/10.3126/ajms.v14i1.48248Keywords:
Doppler; Hammersmith neonatal neurological examination; Hypoxic-ischemic encephalopathyAbstract
Background: Birth asphyxia is a lack of blood flow or gas exchange to or from the fetus in the period immediately before, during, or after the birth process. Birth asphyxia can result in profound systemic and neurologic sequelae due to decreased blood flow and/or oxygen to the developing fetus or infant. Birth asphyxia is one of the most common causes of neonatal mortality and morbidity globally.
Aims and Objectives: The aims of this study were to assess the importance of cranial Doppler as investigation tool for the early prognostic marker of babies with hypoxic-ischemic encephalopathy (HIE) in short term.
Materials and Methods: This prospective study was carried out in a tertiary care teaching hospital. The present study includes 50 newborns, out of which 30 newborns admitted with birth asphyxia were considered as a case, while 20 healthy term newborns were taken as control. Transcranial Doppler of middle cerebral artery (MCA) was done on day 1 of life. They were followed up at discharge for neuromotor outcome by Hammersmith Neonatal neurological examination (HNNE). The outcome was correlated with, Doppler findings of MCA. P<0.05 was taken significant.
Results: Abnormality detected by transcranial Doppler within 24 h of life in neonates with birth asphyxia was significantly associated with poor neuromotor outcome when compared to healthy term neonates. HNNE score in HIE babies was lesser than healthy term neonates on discharge.
Conclusion: Cranial Doppler within 24 h of birth in term HIE babies has very high sensitivity in predicting short-term outcome in babies with HIE, such as Low HNNE score.
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Asian Journal of Medical Sciences
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
