Comparative evaluation of anesthetic efficacy and hemodynamic effects of intrathecal isobaric bupivacaine versus intrathecal isobaric levobupivacaine in the lower abdominal and lower limb surgeries
DOI:
https://doi.org/10.3126/ajms.v13i9.46975Keywords:
Spinal anesthesia; Bupivacaine; LevobupivacaineAbstract
Background: The most frequently utilized approach in patients undergoing lower abdominal and lower limb procedures is spinal anesthesia with bupivacaine.
Aims and Objectives: The aim of the study was to compare the anesthetic efficacy and hemodynamic effects of isobaric bupivacaine and isobaric levobupivacaine for spinal anesthesia.
Materials and Methods: In our study, 80 patients (43 – male and 37 – female) between the ages of 18 and 70 years at Sri Venkateswaraa Medical College Hospital and Research Centre, Ariyur, Puducherry, were enrolled and split into Group I and Group II following approval by an ethical committee and written informed consent. Individuals in Group I were given 3 mL of preservative free 0.5% isobaric bupivacaine (Anawin™, bupivacaine hydrochloride, Neon laboratories, India), and Group II patients were given 3 mL of 0.5% isobaric levobupivacaine (Levoanawin™, levobupivacaine hydrochloride, Neon laboratories, India) for spinal anesthesia. A complete preanesthetic checkup was performed the day before surgery.
Results: In this study, we observed no significant correlation between height, weight, and surgery duration. We discovered a statistically substantial distinction in motor and sensory blockade between the bupivacaine (Group I) and levobupivacaine (Group II) groups. In this study, Group I (50% of patients) had a lower occurrence of hypotension than Group II (20% of patients), indicating a statistically significant variation between the groups.
Conclusion: When compared to levobupivacaine, individuals in the bupivacaine group required more administration of the vasoactive medicine ephedrine and the sympathomimetic drug atropine. Levobupivacaine is less cardiotoxic, neurotoxic, and equally potent local anesthetic compared to its racemate.
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Asian Journal of Medical Sciences
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
