A randomized, controlled, and clinical trial to evaluate the efficacy of electrical vestibular stimulation, compared to a sham control for the management of sleep and autonomic parameters in patients with Parkinson’s disease

Authors

  • Sai Sailesh kumar Goothy Associate Professor, Department of Physiology, R. D. Gardi Medical College, Ujjain, Madhya Pradesh, India https://orcid.org/0000-0002-5838-3994
  • Sudhir Gawarikar Professor, Department of General Medicine, R. D. Gardi Medical College, Ujjain, Madhya Pradesh, India
  • Anita Choudhary Professor and Head, Department of Physiology, R. D. Gardi Medical College, Ujjain, Madhya Pradesh, India
  • Potey Gajanan Govind Professor and Head, Department of Biochemistry, R.D. Gardi Medical College, Ujjain, Madhya Pradesh, India https://orcid.org/0000-0001-8404-7452
  • Manju Purohit Professor and Head, Department of Pathology and Researcher, Department of Global Public Health Sciences, Karolinska Institutet, Stockholm, Sweden https://orcid.org/0000-0001-5385-7305
  • Ashish Pathak Professor, Department of Pediatrics, R.D. Gardi Medical College, Ujjain, Madhya Pradesh, India https://orcid.org/0000-0002-7576-895X
  • Rohit Singh Chouhan Junior Research Fellow, Department of Physiology, R. D. Gardi Medical College, Ujjain, Madhya Pradesh, India https://orcid.org/0000-0003-0631-0184
  • Mahadik Vijay Khanderao Medical Director, R.D. Gardi Medical College, Ujjain, Madhya Pradesh, India

DOI:

https://doi.org/10.3126/ajms.v13i11.46542

Keywords:

Autonomic functions, Non-Motor symptoms, Parkinson’s disease, Sleep, Vestibular stimulation.

Abstract

Background: Electrical vestibular nerve stimulation (VeNs) was simple, non-invasive, and can administer the stimulus in a controlled manner. The studies related to the application of electrical VeNs in the management of sleep and autonomic parameters were sparse in the Indian population.

Aims and Objectives: The present study was undertaken to observe the effectiveness of electrical VeNs in the management of sleep and autonomic parameters in patients with Parkinson’s disease (PD).

Materials and Methods: Thirty cases of PD, both the genders, were recruited in the study by convenient sampling after obtaining written informed consent. After recording baseline parameters of Insomnia Severity Index (ISI), systolic and diastolic blood pressure (DBP), and pulse rate, electrical VeNs was administered to the intervention group and placebo stimulation was administered to the control group for 12 weeks. Post-intervention parameters were recorded after 6 weeks and after 12 weeks after the intervention in both control and intervention groups.

Results: There was a significant decrease in the ISI scores, pulse rate, and systolic blood pressure after the intervention in the participants of the intervention group. DBP was decreased but was not statistically significant. There was no significant difference in the ISI scores, pulse rate, and systolic and DBP before and after the intervention in the participants of the control group.

Conclusion: The present study results support the improvement of sleep followed by electrical VeNs. The study recommends detailed studies in this area to support the incorporation of electrical VeNs in the management strategy of PD.

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Published

2022-11-01

How to Cite

Goothy, S. S. kumar, Gawarikar, S. ., Choudhary, A., Potey Gajanan Govind, Purohit, M., Pathak, A. ., Chouhan, R. S., & Mahadik Vijay Khanderao. (2022). A randomized, controlled, and clinical trial to evaluate the efficacy of electrical vestibular stimulation, compared to a sham control for the management of sleep and autonomic parameters in patients with Parkinson’s disease. Asian Journal of Medical Sciences, 13(11), 203–206. https://doi.org/10.3126/ajms.v13i11.46542

Issue

Vol. 13 No. 11 (2022)

Section

Original Articles

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Copyright (c) 2022 Asian Journal of Medical Sciences

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