Mucinous neoplasms of the appendix - A clinicopathologic study of 21 cases with special insight into current classification & controversies.
DOI:
https://doi.org/10.3126/ajms.v14i1.46093Keywords:
Mucinous neoplasm; Appendix; Low-grade appendiceal mucinous neoplasm; High-grade appendiceal mucinous neoplasmAbstract
Background : Appendiceal mucinous neoplasms are rare and heterogenous disease which often clinically present as appendicitis. There are many controversies regarding the classification of mucinous neoplasms of the appendix.
Aims and Objectives: Our aim of this study was to study different types of mucinous neoplasms of appendix based on current ( WHO 2019) classification, their clinical and radiological presentations and controversies regarding their diagnosis.
Materials and Methods: This was a retrospective study done in a tertiary care hospital. We studied clinical presentations of 21 cases along with the histopathological study of respective appendectomy specimens .
Results: Out of 21 cases, 3 (14.28%) cases were serrated polyp, 9 cases (42.85%) were Low grade appendiceal mucinous neoplasm (LAMN), 3 cases (14.28%) were high grade appendiceal neoplasm (HAMN) and 6 (28.57%) cases were mucinous adenocarcinoma. In this study we have discussed in brief about regarding the current classification and controversies of appendiceal mucinous neoplasms.
Conclusion: Mucinous neoplasms of the appendix are complex lesions with many controversies. Oversimplification in the recent classification may add to more complexity. Reintroduction of the old terminology of Mucinous Tumour of Uncertain Malignant Potential might save histopathologists from potential litigation.
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Asian Journal of Medical Sciences
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
