Directly observed treatment short-course in management of peripheral tubercular lymphadenitis

Authors

DOI:

https://doi.org/10.3126/ajms.v13i8.44004

Keywords:

AFB; CBNAAT; DOTS; Peripheral lymphadenitis; Tuberculosis

Abstract

Background: Tuberculosis (TB) is a major public health problem worldwide. It is one of the main causes of infectious disease and mortality, especially in the developing countries, and has been recognized as one of the top ten causes of death worldwide by the World Health Organization.

Aims and Objectives: The aims of this study were to assess clinical pattern and efficacy of Directly Observed Treatment Short-Course (DOTS) in management of peripheral tubercular lymphadenitis.

Materials and Methods: This was a prospective, observational study among pediatric peripheral tubercular lymphadenitis patients to assess the clinical pattern, investigations, and treatment outcome.

Results: In this study, 72 patients having peripheral tubercular lymphadenitis were enrolled. Most cases had cervical node involvement (81%). Discharging sinus was found in 28.98% cases. Acid-fast bacillus (AFB) was detected by fine needle aspiration and cytology (FNAC) in 21 cases (30.43%). Among them, pulmonary TB was found in two cases (9.52%), one patient being sputum positive. After treatment completion, lymph node(s) enlargement persisted in 6 (8.69%) cases, of which two patients (2.89%) had persistent discharging sinus. On repeat FNAC, acid-fast bacilli were seen in two patients. Success rate was 91.3% confirming the efficacy of DOTS in the management of tubercular lymphadenitis.

Conclusions: Cervical lymphadenitis was found to be most common type of peripheral lymphadenitis. Cytopathology from the suspected lymph nodes had better success rate than AFB detection or CBNAAT of FNAC samples for diagnosing tubercular etiology in the study. DOTS strategy was effective for peripheral tubercular lymphadenitis with high success rate in this study.

Downloads

Download data is not yet available.
Abstract
129
PDF
159

Downloads

Published

2022-08-01

How to Cite

Khuntdar, B. K. ., Roy, A. K. ., Gayen, B. K. ., & Sau, M. (2022). Directly observed treatment short-course in management of peripheral tubercular lymphadenitis. Asian Journal of Medical Sciences, 13(8), 98–102. https://doi.org/10.3126/ajms.v13i8.44004

Issue

Vol. 13 No. 8 (2022)

Section

Original Articles

License

Copyright (c) 2022 Asian Journal of Medical Sciences

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).