Effect of Cigarette Smoking on Plasma Fibrinogen and Platelet Count

Authors

  • Rashmi Narayanrao Gitte Assistant Prof., Department of Physiology, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences & Research Foundation, Chinnaoutpalli

DOI:

https://doi.org/10.3126/ajms.v2i3.4261

Keywords:

Cigarette smoking, Plasma fibrinogen, Platelet count

Abstract

Objective: Cigarette smoking is one of the major lifestyle factors influencing the health of human beings. Fibrinogen is the major plasma protein coagulation factor. Higher plasma fibrinogen concentrations are associated with cardiovascular diseases.

Material & Methods: One hundred twenty healthy male smokers and one hundred twenty healthy male non-smokers among hospital employees and people from surrounding areas of Narayana Medical College, Nellore (India) were studied. The platelet count was done using Beckman Coulter Automatic Analyzer; AcT 5diffCP.Assay for plasma fibrinogen was performed using turbido-metric immunoassay.

Results: The mean plasma fibrinogen concentration for smokers is 3.78 gms/L and for non-smokers 3.02 gms/L. The mean platelet count for smokers is 257325 per mm3 and for non-smokers 215483.3 per mm3. The difference between mean plasma fibrinogen and platelet count of smokers and non-smokers was statistically significant (p<0.0001).

Conclusion: Thus we concluded that in smokers plasma fibrinogen concentration and platelet count increase significantly. Regular monitoring of these two parameters in smokers is advised

DOI: http://dx.doi.org/10.3126/ajms.v2i3.4261

Asian Journal of Medical Sciences 2 (2011) 181-184


 

Downloads

Download data is not yet available.
Abstract
1263
PDF
857

Downloads

Additional Files

Published

2012-04-24

How to Cite

Gitte, R. N. (2012). Effect of Cigarette Smoking on Plasma Fibrinogen and Platelet Count. Asian Journal of Medical Sciences, 2(3), 181–184. https://doi.org/10.3126/ajms.v2i3.4261

Issue

Vol. 2 No. 3 (2011)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).