A retrospective study on the epidemiological and clinical characteristics of SARS-CoV-2 infection among the affected pediatric population attending a tertiary care hospital in Eastern India
DOI:
https://doi.org/10.3126/ajms.v13i2.41891Keywords:
COVID-19, Disease severity, Inflammation, Pediatric population, Retrospective studyAbstract
Background: Novel coronavirus infections cause major morbidity and mortality globally in the all age groups, including the pediatric population. Viral respiratory infections in children may act as a source of infection especially those with asymptomatic SARS-CoV-2 infections.
Aims and Objectives: The aim is to analyze the SARS-CoV-2 characteristics in pediatric age group.
Materials and Methods: Ninety seven children neonate to 5 years age tested positive by RT-PCR were included in the study. Detailed data on socio-demography, epidemiology, clinical characteristics, laboratory findings, comorbidities, management, and outcome of the study population were collected.
Results: Sex distribution showed 47 (48.4%) male and 50 (51.5%) female. Among these 97, 5 children (5.1%) were <28 days of age, 30 children were (31%) neonate to infant age, and 62 children were (63.9%) above 1 year but <5 years of age. The group was divided into two---one with 56 children (57.7%) who were discharged, 2nd with 41 (42.3%) hospitalized children. 1st group was asymptomatic (64.3%)/mildly symptomatic (35.7%). In 2nd group 36.5% were moderately symptomatic, 29.2% were with severe complications, and 34.3% of children were critical--22 (52.6%)
required PICU admission--17 children (41.4%) required mechanical ventilation and 36 (87.8%) required respiratory support.
Conclusion: Reports state that COVID-19 infection is mild in the pediatric population but our findings suggest that some children can develop severe/critical infection requiring hospitalization, respiratory support, and mechanical ventilation.
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