The short term visual, refractive and Topographic outcome of Corneal Collagen Crosslinking in Keratoconus

Authors

  • Renuga Devi Kaliaperumal Assistant Professor, Department of Ophthalmology, Sri Manakula Vinayagar Medical College https://orcid.org/0000-0002-7948-7557
  • Amudha Purushothaman Assistant Professor, Department of Ophthalmology, Indira Gandhi Medical College https://orcid.org/0000-0002-6211-8579
  • Thiruvengada Krishnan Professor and Head, Cornea Clinic, Aravind Eye Hospital, Puducherry, India
  • Shivananda Consultant, Cornea Clinic, Aravind Eye Hospital, Puducherry, India

DOI:

https://doi.org/10.3126/ajms.v12i11.38768

Keywords:

Keratoconus, Collagen cross linking, Riboflavin, UVA irradiation

Abstract

Background: Keratoconus is a condition characterized by biomechanical instability of cornea presenting in a progressive asymmetry and bilateral way. Corneal collagen cross-linking with riboflavin and UVA is a technique that has influenced the treatment of Keratoconus by arresting the progression.

Aims and Objectives: The aim of the study was to assess the short-term efficacy and safety of collagen cross-linking in Keratoconus.

Materials and Methods: This prospective, nonrandomized, interventional case study was conducted at Aravind Eye hospital and PGI, Puducherry from June 2012 to April 2013. Statistical analysis was done using repeated measures ANOVA and Bonferonn’s using IBM SPSS Inc. 20.Version.

Results: A total of 30 patients were enrolled in this study and standard cross linking procedure was done. It was found that UCVA, BSCVA both improved about 40%. Spherical Equivalent reduced by 0.7 D, cylinder reduced by 0.8 D and total astigmatism decreased by about 0.4 D. Steepest K value reduced by 2 D, Irregularity and astigmatism at 3 and 5 mm also changed significantly (P<0.05).

Conclusion: Collagen cross-linking arrests the progression of Keratoconus. It seems to improve the UCVA and BCVA and it is a safe and effective procedure.

Downloads

Download data is not yet available.
Abstract
151
PDF
194

Downloads

Published

2021-11-01

How to Cite

Kaliaperumal, R. D. ., Purushothaman, A. ., Krishnan, T. ., & Shivananda. (2021). The short term visual, refractive and Topographic outcome of Corneal Collagen Crosslinking in Keratoconus. Asian Journal of Medical Sciences, 12(11), 66–70. https://doi.org/10.3126/ajms.v12i11.38768

Issue

Vol. 12 No. 11 (2021)

Section

Original Articles

License

Copyright (c) 2021 Asian Journal of Medical Sciences

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).