Evaluation of Serum 25 Hydroxy Vitamin D level in acute myocardial infarction patients in a tertiary care hospital

Authors

  • Debapriya Rath Assistant Professor, Department of Biochemistry, Pt. J.N.M. Medical College Ayush University, Chhatishgarh http://orcid.org/0000-0003-1908-2416
  • Rachita Nanda Associate Professor, Department of Biochemistry, AIIMS, Raipur, Chattisgarh http://orcid.org/0000-0002-6808-6176
  • Pramila Kumari Mishra Professor and Head, Department of Biochemistry, S.C.B Medical College, Cuttack, Odisha, India
  • Pradeep Kumar Patra Director Professor, Department of Biochemistry, Pt. J.N.M. Medical College Raipur, Ayush University, Chhatishgarh http://orcid.org/0000-0003-4426-0384

DOI:

https://doi.org/10.3126/ajms.v7i6.15699

Keywords:

Vitamin D, Acute myocardial infarction, Diabetes, Hypertension, Obesity

Abstract

Background: Coronary artery disease is the leading cause of death worldwide with acute myocardial infarction being the most severe manifestation. Recent evidences have linked vitamin D in the pathogenesis of the coronary risk factors like diabetes, hypertension, obesity and smoking.

Aims and Objectives: The present study was undertaken with an aim to look for the vitamin D status of the AMI patients and its relation if any with the above mentioned risk factors.

Material and Methods: One hundred acute myocardial infarction patients along with one hundred age and sex matched healthy controls were included in the study and the serum 25 (OH) D was estimated in both the groups.

Results: Serum 25 (OH) Vit D level was found to be lower in cases (19.6±6.85 ng/ml) than in controls (27.5±6.23 ng/ml) (p<0.001).The decreased vitamin D level was associated with the incidence of AMI after adjusting for other risk factors. The serum vitamin D level was significantly decreased in the patients having risk factors among the AMI group.

Conclusion: The present study showed a significantly low serum vitamin D in AMI patients . Given the therapeutic safety and inexpensiveness of vitamin D, further studies may be undertaken to look for the effect of its supplementation on coronary artery disease. 

Asian Journal of Medical Sciences Vol.7(6) 2016 11-15

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Author Biographies

Debapriya Rath, Assistant Professor, Department of Biochemistry, Pt. J.N.M. Medical College Ayush University, Chhatishgarh

assistant professor, department of biochemistry

Rachita Nanda, Associate Professor, Department of Biochemistry, AIIMS, Raipur, Chattisgarh

Associate Professor , Department of Biochemistry

Pramila Kumari Mishra, Professor and Head, Department of Biochemistry, S.C.B Medical College, Cuttack, Odisha, India

Professor , Department of Biochemistry

Pradeep Kumar Patra, Director Professor, Department of Biochemistry, Pt. J.N.M. Medical College Raipur, Ayush University, Chhatishgarh

Professor , Department of Biochemistry

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Published

2016-10-31

How to Cite

Rath, D., Nanda, R., Mishra, P. K., & Patra, P. K. (2016). Evaluation of Serum 25 Hydroxy Vitamin D level in acute myocardial infarction patients in a tertiary care hospital. Asian Journal of Medical Sciences, 7(6), 11–15. https://doi.org/10.3126/ajms.v7i6.15699

Issue

Vol. 7 No. 6 (2016)

Section

Original Articles

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