Postmortem Study of Meloxicam Toxicity in One Month Old Puppy

Authors

  • S. Chalise Nepal Polytechnic Institute, Bharatpur, Chitwan, Nepal
  • D.K. Singh Nepal Polytechnic Institute, Bharatpur, Chitwan, Nepal

DOI:

https://doi.org/10.3126/npijst.v1i1.68948

Keywords:

Meloxicam, puppy, NSAID

Abstract

An intramuscular administration (2.5 mg per kg) of meloxicam caused anorexia, vomiting, and diarrhea within a few hours, followed by unconsciousness, anemia, severe dehydration, and death within 12 hours in a one-month-old puppy. Postmortem findings showed hepatomegaly and acute hemorrhagic inflammation of the abomasum, colon and kidneys. Histological examination revealed tubular hemorrhage and tissue necrosis, with widespread vascular damage in the kidneys. This study emphasized cautious dosing and monitoring of meloxicam in young puppies.

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Published

2024-08-20

How to Cite

Chalise, S., & Singh, D. (2024). Postmortem Study of Meloxicam Toxicity in One Month Old Puppy. NPI Journal of Science and Technology, 1(1), 122–131. https://doi.org/10.3126/npijst.v1i1.68948

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Section

Articles