Hemoglobin: A General Review

Authors

  • Yagya Rath Khadka Patan Multiple Campus, TU, Patandhoka, Lalitpur, Nepal

DOI:

https://doi.org/10.3126/cognition.v3i1.55657

Keywords:

Binding, Derivative, Residue, Concentration, Ligand, Poisoning, Carboxyhemoglobin, Anemia, Bohr’s effect

Abstract

Hemoglobin (Hb) is red blood corpuscle pigment causing red color in blood with centrally located iron atom, responsible for oxygen transport having molecular weight of a tetramer of 64,458 g/mol. The oxygen binding properties of hemoglobin are affected by pH and presence of carbon dioxide. It cause different clinical problems due to its high or low concentration in blood. Poisoning of Hb can also occur by combination of Hb with carbon monoxide resulting in formation of carboxyhemoglobin. Besides carboxyhemoglobin, sulfhemoglobin and methemoglobin are also derivatives of Hb.

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Author Biography

Yagya Rath Khadka, Patan Multiple Campus, TU, Patandhoka, Lalitpur, Nepal

Asst. Professor of Chemistry

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Published

2021-01-30

How to Cite

Khadka, Y. R. (2021). Hemoglobin: A General Review. Cognition, 3(1), 111–118. https://doi.org/10.3126/cognition.v3i1.55657

Issue

Vol. 3 No. 1 (2021): January

Section

Articles