Different Trials in Mechanical Thrombectomy for Acute Ischemic Stroke

Abstract

Acute Ischemic Stroke (AIS) is a leading cause of death and disability. It can be treated
early with a favorable prognosis if intravenous recombinant tissue plasminogen
activator (IV rt-PA) is given to eligible patients within 4.5 hours of its onset. For
those patients who do not meet the criteria to undergo intravenous fibrinolysis,
mechanical thrombectomy has been shown to be an effective alternative in
patients presenting with occlusion of first segment of middle Cerebral artery
(MCA) or of internal carotid artery (ICA), provided the intervention is performed
within 24 hour according to previous trial. We herein review different randomized
controlled trials on AIS undergoing mechanical thrombectomy.