Chemical constituents from <i>Oroxylum indicum</i> (L.) Kurz of Nepalese Origin

Authors

  • Hom Nath Luitel Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu
  • Mina Rajbhandari Research Center for Applied Science and Technology, Tribhuvan University, Kirtipur, Kathmandu
  • Surya K Kalauni Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu
  • Suresh Awale Institute of Natural Medicine, University of Toyama, 2630 Sugitani. Toyama 930-0194
  • Kazuo Masuda Showa Pharmaceutical University, Machida, Tokyo,194
  • Mohan B Gewali Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu

DOI:

https://doi.org/10.3126/sw.v8i8.3852

Keywords:

Oroxylum indicum, Flavones, Baicalein, Brine-shrimp bioassay.

Abstract

From the stem bark of Oroxylum indicum, three flavones namely baicalein (1), oroxylin (2) and pinostrobin (3) along with one sterol, Stigmast-7-en-3-ol (4) were isolated and their structures were established by the use of spectroscopic techniques. Baicalein (1) and oroxylin (2) were found to be active against brine shrimp with LC50 value 10.0 μg/ml and 36.0 μg/ ml and also exhibited the antimicrobial activity on both Gram-positive and Gram-negative bacteria with MIC value 4.0 mg/ml and 8.0 mg/ml respectively.

Key words: Oroxylum indicum; Flavones; Baicalein; Brine-shrimp bioassay.

DOI: 10.3126/sw.v8i8.3852

Scientific World Vol.8(8) 2010 pp.66-68

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How to Cite

Luitel, H. N., Rajbhandari, M., Kalauni, S. K., Awale, S., Masuda, K., & Gewali, M. B. (2010). Chemical constituents from <i>Oroxylum indicum</i> (L.) Kurz of Nepalese Origin. Scientific World, 8(8), 66–68. https://doi.org/10.3126/sw.v8i8.3852

Issue

Vol. 8 No. 8 (2010)

Section

Articles