Castleman Disease: A case report

Abstract

Castleman disease (CD) is a group of lymphoproliferative disorders with common lymph node histological features. It may be either unicentric or multicentric. Unicentric Castleman disease (UCD) is localized and carries an excellent prognosis, whereas multicentric Castleman disease (MCD) is a systemic disease occurring most commonly in the setting of HIV infection and is associated with human herpesvirus 8.¹Castleman disease in the abdomen and pelvis is rare and liable to misdiagnosis, but its characteristic imaging features can help in the diagnosis and differential diagnosis.²Unicentric Castleman disease (UCD) is rare, and there are no reliable estimates of its incidence in the population. While UCD can occur at any age, it is generally a disease of younger adults. The median age at presentation is approximately 35 years.^{3, 4}