Inducible Clindamycin Resistance Among the Staphylococcus aureus Colonizing the Anterior Nares of School Children of Udupi Taluk

Authors

  • S Govindan Senior Grade Lecturer
  • C A Mohammed Professor
  • I Bairy Professor

DOI:

https://doi.org/10.3126/nje.v4i1.10136

Keywords:

Staphylococcus aureus, D test, Inducible clindamycin resistance, MRSA

Abstract

Clindamycin is one of the preferred antibiotics in the treatment of Staphylococcus aureus (SA) skin and soft tissue infections. However the emergence of inducible clindamycin resistant SA is a major concern for clinicians in the management of such infections. Information about such resistant strains of SA colonizing the anterior nares is very important in planning infection control strategies. The objective of the current study was to assess the proportion of SA showing inducible clindamycin resistance and also to know their association with methicillin resistance. Among the isolates, 11.6% (44/378) strains were showing positive D test which indicates inducible clindamycin resistance and a highly significant 71% (12/17) inducible clindamycin resistance was also noticed in the case of MRSA. The nasal carriage of inducible clindamycin resistant SA showing a significant association with MRSA strains by the paediatric population from this area warrants the inclusion of D test in the routine antibiotic susceptibility testing of SA isolates. Information about the MLSBi status among the colonizing strains would also help the public health authorities to plan and implement infection control strategies at the community level.

DOI: http://dx.doi.org/10.3126/nje.v4i1.10136

Nepal Journal of Epidemiology 2014;4 (1): 337-340

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Author Biographies

S Govindan, Senior Grade Lecturer

Department of Microbiology, Melaka Manipal Medical College, Manipal University, Manipal

C A Mohammed, Professor

Department of Microbiology, Melaka Manipal Medical College, Manipal University, Manipal

I Bairy, Professor

Department of Microbiology, Melaka Manipal Medical College, Manipal University, Manipal

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Published

2014-03-29

How to Cite

Govindan, S., Mohammed, C. A., & Bairy, I. (2014). Inducible Clindamycin Resistance Among the Staphylococcus aureus Colonizing the Anterior Nares of School Children of Udupi Taluk. Nepal Journal of Epidemiology, 4(1), 337–340. https://doi.org/10.3126/nje.v4i1.10136

Issue

Vol. 4 No. 1 (2014)

Section

Short Communications

License

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  • Articles in the Nepal Journal of Epidemiology are Open Access articles published under the Creative Commons CC BY License (https://creativecommons.org/licenses/by/4.0/)
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