Limits and chances in an unfortunate course of recurrent orbital rhabdomyosarcoma

Authors

  • J Rustemeyer Department of Oral and Maxillofacial Surgery, Clinic Center Bremen-Mitte, School of Medicine of the University of Göttingen, Bremen
  • L Günther Department of Oral and Maxillofacial Surgery, Clinic Center Bremen-Mitte, School of Medicine of the University of Göttingen, Bremen
  • L Junker Institute of Pathology, Clinic Center Bremen-Mitte, School of Medicine of the University of Göttingen, Bremen

DOI:

https://doi.org/10.3126/nepjoph.v3i2.5279

Keywords:

Orbital rhabdomyosarcoma, recurrence, orbital exenteration

Abstract

Background: Orbital rhabdomyosarcoma (RMS) in childhood has an excellent survival rate after chemotherapy and radiation, and mutilating surgery can often be avoided. Case report: As a rarity we present an unfortunate disease course in a child suffering from orbital embryonal RMS which did not enduringly respond to multimodal therapy including local excision and exenteration orbitae. After short intervals and despite tumor-free margins, orbital RMS recurred twice and led to an extended exenteration orbitae including the bony margins. Because of the lack of standards for adjuvant therapy in cases of recurrences after exenteration orbitae, therapy had to be restricted to a wait- and- see strategy as the only chance of tumor control.

Conclusion: Although survival rates of orbital RMS are high, the possibility of recurrence should not be underestimated. In cases of refractory RMS, new concepts are needed to offer further chances for survival.

Key words: Orbital rhabdomyosarcoma, recurrence, orbital exenteration

DOI: http://dx.doi.org/10.3126/nepjoph.v3i2.5279

Nepal J Ophthalmol 2011; 3(2): 202-205

Downloads

Download data is not yet available.
Abstract
724
PDF
558

Downloads

How to Cite

Rustemeyer, J., Günther, L., & Junker, L. (2011). Limits and chances in an unfortunate course of recurrent orbital rhabdomyosarcoma. Nepalese Journal of Ophthalmology, 3(2), 202–205. https://doi.org/10.3126/nepjoph.v3i2.5279

Issue

Vol. 3 No. 2 (2011)

Section

Case Reports

License

This license enables reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator.