Severe Immune Thrombocytopenic Purpura Treated with Plasma Exchange

Authors

  • MR Sigdel Department of Internal Medicine, TU Teaching Hospital, Kathmandu,
  • DS Shah Department of Internal Medicine, TU Teaching Hospital, Kathmandu,
  • MP Kafle Department of Internal Medicine, TU Teaching Hospital, Kathmandu,
  • KB Raut Department of Internal Medicine, TU Teaching Hospital, Kathmandu,

DOI:

https://doi.org/10.3126/kumj.v10i1.6922

Keywords:

immune thrombocytopenic purpura, intravenous immunoglobulin, plasma exchange

Abstract

Immune thrombocytopenic purpura (ITP) is a hematological disorder characterized by immunologically mediated destruction of platelets and absence of other causes of thrombocytopenia. Treatment is required when the low platelet count entails risk of serious bleeding. Steroid is the first line of management. Acute refractory ITP with very low platelet count is variably treated with high dose steroid, intravenous immunoglobulin (IVIg), anti D or emergency splenectomy. Here, we present a case of steroid resistant ITP with severe thrombocytopenia treated with plasma exchange and low dose IVIg who responded dramatically to the therapy with maintained platelet count till one month from the institution of therapy.

KATHMANDU UNIVERSITY MEDICAL JOURNAL  VOL.10 | NO. 1 | ISSUE 37 | JAN - MAR 2012 | 85-87

DOI: http://dx.doi.org/10.3126/kumj.v10i1.6922

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Published

2012-10-02

How to Cite

Sigdel, M., Shah, D., Kafle, M., & Raut, K. (2012). Severe Immune Thrombocytopenic Purpura Treated with Plasma Exchange. Kathmandu University Medical Journal, 10(1), 77–82. https://doi.org/10.3126/kumj.v10i1.6922

Issue

Vol. 10 No. 1 (2012)

Section

Case Notes