Antimicrobial Susceptibilty Profile of Urinary Tract Infection: A Single Centre Hospital Based Study From Nepal

Authors

  • Sulochana Khatiwada Department of Microbiology, Universal College of Medical Sciences & Teaching Hospital, Bhairahawa
  • Rita Khanal Department of Microbiology, Universal College of Medical Sciences & Teaching Hospital, Bhairahawa
  • Subhash Lal Karn Department of Microbiology, Universal College of Medical Sciences & Teaching Hospital, Bhairahawa
  • Shristi Raut Department of Microbiology, Universal College of Medical Sciences & Teaching Hospital, Bhairahawa
  • Anuj Poudel Department of Pathology, Universal College of Medical Sciences & Teaching Hospital, Bhairahawa

DOI:

https://doi.org/10.3126/jucms.v6i2.22477

Keywords:

Antimicrobial susceptibility profile, urinary tract infection, Nepal

Abstract

Introduction: Urinary tract infection (UTI) is amongst the most common bacterial infections. Identification of causative organism and their in-vitro susceptibility test is essential for the successful treatment of a patient. The study was done to determine different bacterial species causing UTI and their antimicrobial susceptibility profile.

 Materials and methods: A total of 332 urine samples from patients attending both inpatient and outpatient departments of UCMS-TH were included in this study. Samples were subjected to culture and sensitivity test with the use of standard bacteriological techniques as described by American Society for Microbiology (ASM).

 Results Twenty three percent of the total urine samples showed significant bacterial growth. Thirteen different bacterial species were isolated. Among these, Escherichia coli (50.6%) was the most predominant one followed by Klebsiella species (15.6%), Staphylococcus aureus (7.8%) and others.  Majority of bacteria isolated was found to be sensitive to imipenem (82%) followed by nitrofurantoin (78%), gentamicin (63.8%) and others.

 Conclusion: UTI is a commonly encountered case in general practice. Females are commonly affected than males. Majority of bacterial isolates were found resistant towards commonly used first line antimicrobial agents. This type of study should be continued to determine the changing pattern of microbial flora and their antibiogram.

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Published

2018-12-03

How to Cite

Khatiwada, S., Khanal, R., Karn, S. L., Raut, S., & Poudel, A. (2018). Antimicrobial Susceptibilty Profile of Urinary Tract Infection: A Single Centre Hospital Based Study From Nepal. Journal of Universal College of Medical Sciences, 6(2), 37–40. https://doi.org/10.3126/jucms.v6i2.22477

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Section

Original Articles