Prevalence of Helicobacter Pylori Infection in Patients with Portal Hypertension

Authors

  • Shatdal Chaudhary Department of Internal Medicine, Universal College of Medical Sciences, Bhairahawa
  • Altaban Rahi Department of Medicine, Bheri Zonal Hospital, Nepalgunj
  • Anita Shah Department of Pathology, Universal College of Medical Sciences, Bhairahaw
  • Aakash Shahi Department of Internal Medicine, Universal College of Medical Sciences, Bhairahawa
  • Badri Kumar Gupta Department of Pediatrics, Universal College of Medical Sciences, Bhairahawa
  • Niraj Kumar Jaiswal Department of Internal Medicine, Universal College of Medical Sciences, Bhairahawa

DOI:

https://doi.org/10.3126/jucms.v6i2.22470

Keywords:

Chronic liver disease, Helicobacter pylori, portal hypertension, rapid urease test

Abstract

Introduction: Helicobacter pylori (H. pylori) is a microaerophile gram-negative bacillus which is found mainly on the surface of mucous membrane of the prepyloric part of the stomach. It is found to be infecting approximately 50% of world population. In patients with liver cirrhosis, the prevalence of H. pylori is variable. A high incidence of H. pylori colonization has been found in portal hypertension; especially in those with gastric erosion. This study was done to find out the prevalence of H. pylori infection in patients with portal hypertension at Universal College of Medical Sciences Teaching Hospital, Nepal.

 Materials and methods: It was a hospital based cross sectional observational study. All the consecutive patients aged more than 16 years, presented with portal hypertension who fulfilled the inclusion criteria were included in the study. The study period was from 1st  September 2015 to 31st August 2016. The upper gastrointestinal endoscopy was done in all cases and mucosal biopsy was taken. H. pylori infection was diagnosed by using rapid urease test.

 Results: During the study period, 71 patients fulfilled the inclusion criteria and were included in the analysis. The majority of the patients 21 (29.6%) were between 51-60 years age group. There were more male (78.9%) then female (21.1%). The mean age of study population was 50.85 ± 12.47 years. Among the study population, rapid urease test was positive in 70.4% (n=50) patients.

 Conclusion: The prevalence of H. pylori infection was seen in 70.4% of the patients suffering with portal hypertension. 

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Published

2018-12-03

How to Cite

Chaudhary, S., Rahi, A., Shah, A., Shahi, A., Gupta, B. K., & Jaiswal, N. K. (2018). Prevalence of Helicobacter Pylori Infection in Patients with Portal Hypertension. Journal of Universal College of Medical Sciences, 6(2), 16–19. https://doi.org/10.3126/jucms.v6i2.22470

Issue

Vol. 6 No. 2 (2018)

Section

Original Articles

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