Presentation, Treatment and Outcomes of Acute Coronary Syndrome in a Tertiary Care Hospital in Central Nepal

Authors

  • Murari Prasad Barakoti Department of Cardiology, Chitwan Medical College Teaching Hospital, Bharatpur, Chitwan
  • S R Regmi Department of Cardiology, Chitwan Medical College Teaching Hospital, Bharatpur, Chitwan
  • B M Dhital Department of Cardiology, Chitwan Medical College Teaching Hospital, Bharatpur, Chitwan

DOI:

https://doi.org/10.3126/jucms.v2i4.12036

Keywords:

Acute coronary syndrome, Outcomes

Abstract

INTRODUCTION: Nepal is facing with increasing rate of coronary artery disease, yet little is known about presentation, treatment and outcome of this disease in our population and our setting. We aimed to document the characteristics in consecutive cases in a tertiary level hospital. 

MATERIAL AND METHODS: Seventy eight total cases were documented in six months period and evaluated the data on presentation, management, in-hospital mortality and non-fatal adverse cardiovascular event (MACE). 

RESULTS: Mean (SD) age at presentation was 65 (13) years and did not differ among acute coronary syndrome (ACS) types (STEMI= 23%, Non ST Elevation Myocardial Infarction (NSTEMI)= 28%, UA= 49%). ACS is still a disease prevalent in >50 years of age (88%). Dual antiplatelet agents and statin were used >90% cases and coronary angiography was performed in ~50% cases. Unstable angina patients has significantly higher number of normal coronaries or non- critical stenosis. Percutaneous coronary intervention rates were significantly higher among STEMI admissions (38% vs

22 % vs 13%, P= 0.003). Unadjusted in-hospital mortality rate was 11%, significantly higher than NSTEMI (5%) and UA (5%). Non-fatal major MACE rate including reinfarction, heart failure or cardiogenic shock was also high in STEMI and NSTEMI patients than in unstable angina patients. 

CONCLUSION: This study represents contemporary practice of ACS care and provides opportunity to improve care for symptom recognition, treatment options and medical therapy.

DOI: http://dx.doi.org/10.3126/jucms.v2i4.12036

Journal of Universal College of Medical Sciences (2014) Vol.02 No.04 Issue 08

Page: 11-14

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Author Biographies

Murari Prasad Barakoti, Department of Cardiology, Chitwan Medical College Teaching Hospital, Bharatpur, Chitwan

Associate Professor

S R Regmi, Department of Cardiology, Chitwan Medical College Teaching Hospital, Bharatpur, Chitwan

Professor

B M Dhital, Department of Cardiology, Chitwan Medical College Teaching Hospital, Bharatpur, Chitwan

Assistant Professor

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Published

2015-02-05

How to Cite

Barakoti, M. P., Regmi, S. R., & Dhital, B. M. (2015). Presentation, Treatment and Outcomes of Acute Coronary Syndrome in a Tertiary Care Hospital in Central Nepal. Journal of Universal College of Medical Sciences, 2(4), 11–14. https://doi.org/10.3126/jucms.v2i4.12036

Issue

Vol. 2 No. 4 (2014)

Section

Original Articles

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