Carcinosarcoma of lung

Authors

  • S Neupane Department of Pathology, B. P Koirala Memorial Cancer Hospital, Bharatpur,
  • T Pathak Department of Pathology, B. P Koirala Memorial Cancer Hospital, Bharatpur,
  • S Bastola Department of Pathology, B. P Koirala Memorial Cancer Hospital, Bharatpur,
  • S Shrestha Department of Pathology, B. P Koirala Memorial Cancer Hospital, Bharatpur,
  • CB Pun Department of Pathology, B. P Koirala Memorial Cancer Hospital, Bharatpur,

DOI:

https://doi.org/10.3126/jpn.v3i5.7873

Keywords:

Carcinosarcoma, Lung, Malignant, Spindle cells

Abstract

Primary carcinosarcoma of the lung is exceedingly rare. It is described as malignancy composed of a mixture of carcinoma and sarcoma elements. The sarcomatous element is usually spindle cell but may contain cartilage, bone or skeletal muscle. We report a case of pulmonary carcinosarcoma in a 66 years male who presented with cough, chest pain on exertion, anorexia and weight loss. Brush cytology revealed poorly differentiated non-small cell carcinoma. Histopathological examination showed proliferation of malignant spindle cells containing bone and malignant cartilage admixed with areas of keratinized squamous cells with few foci of ill-defined glandular structure. On immunohistochemistry, carcinomatous component of tumor showed positivity for cytokeratin AE1/AE3 and spindle cell component were positive for vimentin. These findings led to diagnosis of carcinosarcoma.

Journal of Pathology of Nepal (2013) Vol. 3, No.1, Issue 5, 419-421

DOI: http://dx.doi.org/10.3126/jpn.v3i5.7873

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Published

2013-03-27

How to Cite

Neupane, S., Pathak, T., Bastola, S., Shrestha, S., & Pun, C. (2013). Carcinosarcoma of lung. Journal of Pathology of Nepal, 3(5), 419–421. https://doi.org/10.3126/jpn.v3i5.7873

Issue

Vol. 3 No. 5 (2013)

Section

Case Reports

License

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