Direct immunofluorescence in bullous disorders: A mini-review

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DOI:

https://doi.org/10.3126/jpn.v14i1.67851

Keywords:

Blistering; Bullous; FITC; Immunofluorescence; Immunoglobulins

Abstract

Background: Immunofluorescence microscopy is an invaluable tool for different lesions in dermatopathology.  These lesions include bullous lesions, vasculitis, and connective tissue disorders/systemic lupus erythematosus.  In this review, we take a look at bullous disorders. 

Some of these diagnoses are not possible on routine histopathology alone and require immunofluorescence for confirmation.  Different diseases can be diagnosed according to the immunoglobulins/complements, sites of deposition (dermo-epidermal / intercellular spaces / dermal), and their patterns (linear, granular).  Knowing the exact type of lesion can help guide treatment accordingly.

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Author Biography

Anil Dev Pant, T. U. Teaching Hospital, Maharajgunj, Kathmandu, Nepal

Associate Professor, Department of Pathology

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Published

2024-10-15

How to Cite

Pant, A. D. (2024). Direct immunofluorescence in bullous disorders: A mini-review. Journal of Pathology of Nepal, 14(1), 2167–2170. https://doi.org/10.3126/jpn.v14i1.67851

Issue

Vol. 14 No. 1 (2024)

Section

Review Articles

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Copyright (c) 2024 The Author(s)

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