Bruton’s X-Linked Agammaglobulinemia Presenting as Chronic Monoarticular Arthritis

Authors

  • Mani Kant Kumar Assistant Professor, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar
  • Pankaj Kumar Patel Assistant Professor, Department of Pathology, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar
  • Mohammad Mahtab Ali Tahir Junior Resident, Department of Paediatrics, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar

DOI:

https://doi.org/10.3126/jnps.v32i3.6183

Keywords:

Bruton’s X-linked Agammaglobulinemia, Chronic monoarticular arthritis, Btk gene

Abstract

Bruton’s X-Linked Agammaglobulinemia (XLA) is an X linked recessive primary immune deficiency disorder characterized by recurrent bacterial infections and failure to generate immunoglobulins of all isotypes due to the absence or profoundly decreased mature B cells and plasma cells, secondary to mutations in the Bruton’s tyrosine kinase (Btk) gene. The coexistence of chronic monoarticular arthritis in a patient with Bruton’s XLA has been described an uncommon presentation. We describe a 5 year-old boy with XLA and chronic monoarticular arthritis.

DOI: http://dx.doi.org/10.3126/jnps.v32i3.6183

J. Nepal Paediatr. SocVol.32(3) 2012 245-249

Downloads

Download data is not yet available.
Abstract
1109
PDF
762

Downloads

Additional Files

Published

2013-02-23

How to Cite

Kumar, M. K., Patel, P. K., & Tahir, M. M. A. (2013). Bruton’s X-Linked Agammaglobulinemia Presenting as Chronic Monoarticular Arthritis. Journal of Nepal Paediatric Society, 32(3), 245–249. https://doi.org/10.3126/jnps.v32i3.6183

Issue

Vol. 32 No. 3 (2012)

Section

Brief Reports/Case Reports/Case Series

License

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).