Study of Vitamin D Level in Paediatric Asthma at a Tertiary care Center

Authors

  • Pankaj Kumar Professor, Department of Paediatrics, S.N. Medical College, Agra, UP, India
  • Rajesh Kumar Professor, Department of Paediatrics, S.N. Medical College, Agra, UP, India
  • Pratap Bhanu Singh Junior Resident, Department of Paediatrics, S.N. Medical College, Agra, UP, India

DOI:

https://doi.org/10.3126/jnps.v42i3.47355

Keywords:

Allergy; Asthma; Vitamin D deficiency

Abstract

Introduction: There are few studies that suggest low Vitamin D levels are associated with asthma. Present study was conducted to evaluate the association between vitamin D levels with asthma and its severity in children.

Methods: This cross-sectional study included 70 children (35 asthmatic and 35 controls) aged between three to 12 yrs. CBC, AEC, IgE, spirometry, chest X-ray, and serum vitamin D levels were measured. Vitamin D levels were categorized according to guidelines of the American Academy of Paediatrics (2008) and compared between the two groups. The association between vitamin-D levels with asthma and its severity was studied.

Results: The mean age of study group cases was 9.23 ± 2.62 yr. The male:female ratio in the study group was 2.5: 1. Cough and wheezing was the commonest manifestation (100%). Most of the patients had mild asthma (45.71%). Asthma was more common in the urban population (68.57%) and children belonging to lower socioeconomic status (51.43%). The markers of allergic disorders {Eosinophils, AEC and IgE} were elevated (all p-values ≤ 0.0001) in study group. Mean serum vitamin D levels in the study group and control group patients were 45.21 ± 28.52 nmol/L and 57.03 ± 40.01 nmol / L respectively. The mean levels of vitamin D in the study group were insufficient as per AAP criteria. Vitamin D levels were more deficient in severe asthma (26.19 ± 14.46 nmol/L).

Conclusions: In the present study Vitamin D insufficiency was seen in patients with asthma.

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Published

2022-12-31

How to Cite

Kumar, P., Kumar, R., & Singh, P. B. (2022). Study of Vitamin D Level in Paediatric Asthma at a Tertiary care Center. Journal of Nepal Paediatric Society, 42(3), 56–60. https://doi.org/10.3126/jnps.v42i3.47355

Issue

Vol. 42 No. 3 (2022)

Section

Original Articles

License

Copyright (c) 2022 Pankaj kumar, Rajesh Kumar, Pratap Bhanu Singh

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