Vitamin B12 Deficiency Presenting as Pancytopenia with Hepatosplenomegaly in an Infant

Authors

  • Prerana Gauchan Department of Paediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal 
  • Bishnu Rath Giri Hemato-oncology Unit, Department of Paediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal 
  • Uma Bhatta Department of Pathology, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal 

DOI:

https://doi.org/10.3126/jnps.v40i1.28737

Keywords:

Hepatosplenomegaly, pancytopenia, vitamin B12

Abstract

Deficiency of vitamin B12 due to nutritional insufficiency is common in developing part of world. Serum vitamin B12 level in infants is determined by the foetal storage during pregnancy. Therefore, evaluation on vitamin B12 level during pregnancy is essential for prevention of vitamin B12 deficiency in infancy. Here we report a vitamin B12 deficient infant who presented with hepatosplenomegaly with pancytopenia including normocytic anaemia and circulating atypical cells. It is also a reminder to clinicians about the uncommon manifestation of vitamin B12 deficiency which mimics haematological malignancy.

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Published

2020-08-10

How to Cite

Gauchan, P., Giri, B. R., & Bhatta, U. (2020). Vitamin B12 Deficiency Presenting as Pancytopenia with Hepatosplenomegaly in an Infant. Journal of Nepal Paediatric Society, 40(1), 60–63. https://doi.org/10.3126/jnps.v40i1.28737

Issue

Vol. 40 No. 1 (2020)

Section

Case Reports

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