Intracranial Hemorrhage Caused by Vitamin K Deficiency Beyond Neonatal Period

Authors

  • Sudhir Adhikari Manipal College of Medical Sciences, Pokhara
  • Eva Gauchan Manipal College of Medical Sciences, Pokhara
  • Tejesh Malla Manipal College of Medical Sciences, Pokhara
  • Brijesh Sathian Manipal College of Medical Sciences, Pokhara
  • Kalipatanam Seshagiri Rao Manipal College of Medical Sciences, Pokhara

DOI:

https://doi.org/10.3126/jnps.v37i1.16301

Keywords:

Intracranial haemorrhage-Late onset haemorrhagic disease of newborn -Vitamin K

Abstract

Vitamin K deficiency bleeding (VKDB) can manifest as intracranial hemorrhage (ICH) and is still prevalent in poor resource countries. Infants aged one to twelve months with the diagnosis of ICH from 1st July 2011 to 30th June 2016 were included. There were 16 cases of ICH attributed to vitamin K deficiency. Clinical presentations were anemia16 (100%), bulged fontanel 13(81.3%), seizures 10(62.5%), vomiting 8(50%) and fever 9(56.3%). Mean INR at admission was 8.575±7.267 and 1.868±0.838 after three doses of vitamin K administration. Sites of intracranial bleed were parenchymal 5(31.3%), subdural 4(25%), extradural 2(12.5%), ventricular 2(12.5%). In 3(18.8%) of cases bleeding was more extensive involving more than one site. Mortality was 4(25%) and 3(18.8%) had abnormal neurological findings at discharge. There is an urgent need for national policy for vitamin K prophylaxis at birth.

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Author Biographies

Sudhir Adhikari, Manipal College of Medical Sciences, Pokhara

Assistant Professor, Department of Pediatrics

Eva Gauchan, Manipal College of Medical Sciences, Pokhara

Associate Professor,
Department of Paediatrics

Tejesh Malla, Manipal College of Medical Sciences, Pokhara

Associate Professor, Department of Paediatrics

Brijesh Sathian, Manipal College of Medical Sciences, Pokhara

Assistant, Department of community medicine

Kalipatanam Seshagiri Rao, Manipal College of Medical Sciences, Pokhara

Professor of Paediatrics

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Published

2017-10-04

How to Cite

Adhikari, S., Gauchan, E., Malla, T., Sathian, B., & Rao, K. S. (2017). Intracranial Hemorrhage Caused by Vitamin K Deficiency Beyond Neonatal Period. Journal of Nepal Paediatric Society, 37(1), 104–107. https://doi.org/10.3126/jnps.v37i1.16301

Issue

Vol. 37 No. 1 (2017)

Section

Case Series

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