A Review: Lantibiotics, a Promising Antimicrobial Agent

Authors

  • Shradha Basi-Chipalu SANN International College, Gairidhara, Kathmandu

DOI:

https://doi.org/10.3126/jist.v21i1.16063

Keywords:

Lantibiotics, Gene cluster, Posttranslational modification, Antibiotic resistant

Abstract

Rise  in  multi  drug  resistant  bacteria  has  been  a  public  health  problem.  This has necessitated for the exploration of novel antimicrobials. Bacteriocins, probiotic bacteria, and bacteriophages are considered as alternatives to antibiotics. To this context, lantibiotics could be the future candidate for antimicrobial agent.Lantibiotics are synthesized ribosomally and  after posttranslational modification  active peptide is produced.Lantibiotics are lanthionine and methyllanthionine containing peptides exhibiting activity against multi drug resistant  pathogens. Besides its application  as  alternatives  to  old  antibiotics, they can be used as food preservatives, additives, probiotics, and prophylactics.

Journal of Institute of Science and Technology

Volume 21, Issue 1, August 2016, Page: 119-128

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Published

2016-11-24

How to Cite

Basi-Chipalu, S. (2016). A Review: Lantibiotics, a Promising Antimicrobial Agent. Journal of Institute of Science and Technology, 21(1), 119–128. https://doi.org/10.3126/jist.v21i1.16063

Issue

Vol. 21 No. 1 (2016)

Section

Review Articles

License

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