Variation in the active constituent contents in <i>Centella asiatica</i> grown in different habitats in Nepal

Authors

  • Anjana Devkota Central Department of Botany, Tribhuvan University, Kirtipur, Kathmandu
  • Stefano Dall' Acqua Department of Pharmaceutical Sciences, University of Padova, Padova
  • Pramod Kumar Jha Central Department of Botany, Tribhuvan University, Kirtipur, Kathmandu
  • Gabbriel Innocenti Department of Pharmaceutical Sciences, University of Padova, Padova

DOI:

https://doi.org/10.3126/botor.v7i0.4372

Keywords:

Asiaticoside, asiatic acid, Centella asiatica, HPLC, medicinal plants, quercetin 3-O-glucuronide

Abstract

Centella asiatica is an important medicinal plant of subtropical to tropical region. It grows widely, in different habitats. In Nepal, it is distributed at an altitudinal range of 96-2200 m above sea level. A comparative quantitative analysis of chemical constituents in Centella asiatica samples collected from three different habitats in Nepal was carried out by HPLC to evaluate the variability in the important constituents. There was marked variability in asiaticoside, asiatic acid and quercetin 3-O-glucuronide content among the samples collected from different habitats. Samples collected from open agricultural land showed the highest asiaticoside (1.91%), asiatic acid (0.13%) and quercetin 3-O-glucuronide (0.35%) content. Therefore, open land is preferable for plantation of this species for high yield of secondary metabolites.

Key-words: Asiaticoside; asiatic acid; Centella asiatica; HPLC; medicinal plants; quercetin 3-O-glucuronide.

DOI: 10.3126/botor.v7i0.4372

Botanica Orientalis – Journal of Plant Science (2010) 7: 43-47

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How to Cite

Devkota, A., Acqua, S. D., Jha, P. K., & Innocenti, G. (2011). Variation in the active constituent contents in <i>Centella asiatica</i> grown in different habitats in Nepal. Botanica Orientalis: Journal of Plant Science, 7, 43–47. https://doi.org/10.3126/botor.v7i0.4372

Issue

Vol. 7 (2010)

Section

Research

License

© Central Department of Botany, Tribhuvan University, Botanica Orientalis