Phytochemical Screening and Biological Activities of Oxalis corniculata Leaves of Sindhupalchowk District, Nepal

Authors

  • Kamala Pandey Department of Chemistry, Tri-Chandra Multiple Campus, Tribhuvan University, Kathmandu, Nepal
  • Shanta Pokhrel Department of Chemistry, Tri-Chandra Multiple Campus, Tribhuvan University, Kathmandu, Nepal

DOI:

https://doi.org/10.3126/bibechana.v19i1-2.46094

Keywords:

Antibacterial, Antioxidant, IC50, Phytochemical screening

Abstract

The Oxalis corniculata (Oxalidaceae) is one of the most potential medicinal herbs and well known for multiple therapeutic properties (anti-inflammatory, anticancer, antioxidant, antimicrobial, analgesic and diuretic activity). This study investigated phytoconstituents, antibacterial activity and antioxidant activity of Oxalis corniculata leaves extract. Methanol based phytochemical screening of Oxalis corniculata revealed the presence of alkaloids, proteins, phenols, flavonoids, glycosides. The antibacterial activity revealed better potential inhibitory effect against gram-negative bacteria, particularly Escherichia coli and Salmonella typhi compared to Staphylococcus aureus, a gram-positive bacterium. However, 1% methanol extract showed highest antibacterial activity against Escherichia coli followed by Staphylococcus aureus and Salmonella typhi. Antioxidant activity of the methanol extract with 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging showed antioxidant activities with 3.87 µg/mL IC50 value.

BIBECHANA 19 (2022) 27-33

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Published

2022-09-12

How to Cite

Pandey, K., & Pokhrel, S. (2022). Phytochemical Screening and Biological Activities of Oxalis corniculata Leaves of Sindhupalchowk District, Nepal. BIBECHANA, 19(1-2), 27–33. https://doi.org/10.3126/bibechana.v19i1-2.46094

Issue

Vol. 19 No. 1-2 (2022)

Section

Research Articles

License

Copyright (c) 2022 Kamala Pandey, Shanta Pokhrel

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.