Elevated serum uric acid and triglycerides level in the patients with Type II Diabetes Mellitus- a Nepalese case control study

Authors

  • Hridaya Parajuli Department of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu
  • Jyotsna Shakya Department of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu
  • Bashu Dev Pardhe Department of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu
  • Puspa Raj Khanal Department of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu
  • Narayan Prasad Parajuli Department of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu
  • Pooja Maharjan Department of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu
  • Govardhan Joshi Department of Laboratory Medicine, Manmohan Memorial Institute of Health Sciences, Kathmandu
  • Alneil Mohamad Hamza College of Applied Medical Sciences Al Jouf University
  • Dipendra Raj Pandeya College of Applied Medical Sciences Al Jouf University, Saudi Arabia Department of Biochemistry, College of Medicine, Nepalese Army Institute of Health Sciences

DOI:

https://doi.org/10.3126/acclm.v2i2.15590

Keywords:

Hyperuricemia, Hypertriglyceridemia, Type II Diabetes Mellitus

Abstract

Background: Hyperuricemia is associated with type 2 diabetes, which is a metabolic disorder of multiple etiologies resulting from defects in insulin action. The present study wascarried out to look for any association between uric acid and Type II Diabetes Mellitus and also status of triacylglycerol level among those patients.

Methods: The blood samples were collected 100 diabetic and 100 non-diabetic individuals in the department of biochemistry and then analyzed for estimation of blood glucose, Uric Acid and Triacylglycerol level.

Results: The average level of serum uric acid in diabetic patients was higher (5.706±1.617) in comparison to non diabetic subjects (4.322±0.784) with statistically significant difference (p≤0.05). For female the result indicate there was a positive correlation between (FBS and triglycerides) and (triglycerides and uric acids) which was statistically significant (r =-0.465, n = 41, p = 0.002) and(r =-0.370, n = 41, p = 0.017) respectively.

Conclusions: This study documents that hyperuricemia is associated with type 2 diabetes mellitus. Furthermore, the serum triacylglycerol and serum uric acid is also found to be associated risk factors for diabetic complications. Hence, timely diagnosis and management of diabetes is vital to control the complications related to diabetes.

Ann. Clin. Chem. Lab. Med. 2016:2(1); 26-34

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Author Biography

Alneil Mohamad Hamza, College of Applied Medical Sciences Al Jouf University

Department of Biochemistry

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Published

2017-03-31

How to Cite

Parajuli, H., Shakya, J., Pardhe, B. D., Khanal, P. R., Parajuli, N. P., Maharjan, P., Joshi, G., Hamza, A. M., & Pandeya, D. R. (2017). Elevated serum uric acid and triglycerides level in the patients with Type II Diabetes Mellitus- a Nepalese case control study. Annals of Clinical Chemistry and Laboratory Medicine, 2(2), 26–34. https://doi.org/10.3126/acclm.v2i2.15590

Issue

Vol. 2 No. 2 (2016)

Section

Original Articles

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